Hitomi Kanno Selected Research

Yi-Gan San

1/2022	Impact of Gut Microbiota on the Pharmacokinetics of Glycyrrhizic Acid in Yokukansan, a Kampo Medicine.
1/2015	Protective effects of glycycoumarin and procyanidin B1, active components of traditional Japanese medicine yokukansan, on amyloid β oligomer-induced neuronal death.
1/2014	Yokukansan, a kampo medicine, protects PC12 cells from glutamate-induced death by augmenting gene expression of cystine/glutamate antiporter system Xc-.
8/2013	Glycyrrhiza and Uncaria Hook contribute to protective effect of traditional Japanese medicine yokukansan against amyloid β oligomer-induced neuronal death.
12/2012	Ameliorative effect of yokukansan on vacuous chewing movement in haloperidol-induced rat tardive dyskinesia model and involvement of glutamatergic system.
4/2011	Effects of yokukansan and donepezil on learning disturbance and aggressiveness induced by intracerebroventricular injection of amyloid β protein in mice.
3/2011	Yokukansan, a kampo medicine, protects against glutamate cytotoxicity due to oxidative stress in PC12 cells.
10/2010	Electron-microscopic examination of effects of yokukansan, a traditional Japanese medicine, on degeneration of cerebral cells in thiamine-deficient rats.
10/2009	Effects of yokukansan, a traditional Japanese medicine, on memory disturbance and behavioral and psychological symptoms of dementia in thiamine-deficient rats.
9/2009	Effect of yokukansan, a traditional Japanese medicine, on social and aggressive behaviour of para-chloroamphetamine-injected rats.

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Hitomi Kanno Research Topics

Disease

4	Dementia (Dementias) 01/2022 - 10/2009
4	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2015 - 09/2009
3	Neoplasms (Cancer) 05/2007 - 05/2003
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022 - 09/2020
2	Inflammation (Inflammations) 01/2022 - 01/2017
2	Learning Disabilities (Learning Disability) 04/2011 - 10/2010
2	Prostatic Neoplasms (Prostate Cancer) 03/2008 - 05/2006
2	Renal Cell Carcinoma (Grawitz Tumor) 09/2007 - 04/2007
2	Adenocarcinoma 05/2007 - 05/2006
2	Margins of Excision 05/2007 - 05/2006
1	Infections 01/2022
1	Obstructive Jaundice (Cholestatic Jaundice) 01/2022
1	Delirium 01/2022
1	Common Cold 09/2020
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 03/2020
1	Cushing Syndrome 03/2020
1	Pain (Aches) 03/2020
1	Body Weight (Weight, Body) 01/2017
1	Pheochromocytoma 01/2014
1	Tardive Dyskinesia 12/2012
1	Thiamine Deficiency 10/2010
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 12/2008
1	Lower Urinary Tract Symptoms 12/2008
1	Migraine with Aura (Familial Hemiplegic Migraine) 09/2008
1	Migraine Disorders (Migraine) 09/2008
1	Hypercalcemia (Milk Alkali Syndrome) 09/2007
1	Ductal Carcinoma 05/2007
1	Dysuria 05/2007
1	Hyperthyroidism 04/2007
1	Thyroid Diseases (Thyroid Disease) 04/2007
1	Weight Loss (Weight Reduction) 04/2007
1	Hepatitis C 04/2007
1	Hydronephrosis 01/2007
1	Carcinoma (Carcinomatosis) 05/2006
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 05/2003
1	Azoospermia 05/2003
1	Testicular Neoplasms (Testicular Cancer) 05/2003

Drug/Important Bio-Agent (IBA)

10	Yi-Gan SanIBA 01/2022 - 09/2009
2	15- methyl- 8- aza- 16- oxagona- 1,3,5(10),13- tetraen- 17- one (MAOTO)IBA 01/2022 - 01/2017
2	Pharmaceutical PreparationsIBA 01/2017 - 09/2007
2	Prostate-Specific Antigen (Semenogelase)IBA 03/2008 - 05/2007
1	CytokinesIBA 01/2022
1	genipinIBA 01/2022
1	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2020
1	GlucocorticoidsIBA 03/2020
1	Toll-Like Receptor 3IBA 01/2017
1	AntiportersIBA 01/2014
1	Glutamic Acid (Glutamate)FDA Link 01/2014
1	Cystine (L-Cystine)IBA 01/2014
1	Haloperidol (Haldol)FDA LinkGeneric 12/2012
1	haloperidol decanoate FDA LinkGeneric 12/2012
1	Donepezil (Aricept)FDA LinkGeneric 04/2011
1	Amyloid (Amyloid Fibrils)IBA 04/2011
1	Proteins (Proteins, Gene)FDA Link 04/2011
1	Thiamine (Aneurin)FDA Link 10/2009
1	silodosin FDA Link 12/2008
1	goshuyu-toIBA 09/2008
1	Acetates (Acetic Acid Esters)FDA Link 09/2007
1	Capsules (Microcapsules)IBA 05/2007
1	Interferon-alpha (Interferon Alfa)IBA 04/2007
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 04/2007

Therapy/Procedure

6	Kampo Medicine (Kampo) 01/2022 - 08/2013
4	Therapeutics 03/2020 - 05/2006
2	Prostatectomy (Retropubic Prostatectomy) 03/2008 - 05/2006
2	Transurethral Resection of Prostate (TURP) 05/2007 - 05/2006
1	Intraperitoneal Injections 01/2022
1	Traditional Medicine (Folk Remedies) 09/2020
1	Adrenalectomy 03/2020
1	Nephrectomy 09/2007
1	Catheters 01/2007
1	Drug Therapy (Chemotherapy) 05/2003